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Hotel Accommodations & Amenities

Experience a truly sophisticated and contemporary Key West hotel when you choose the Santa Maria Suites Resort. Barely a block from the Atlantic Ocean and Duval Street, our elegantly refined all-suites Key West accommodations are nothing short of breathtaking. The charm of Key West along with spacious Key West hotel suites and gracious amenities await you at our Key West, Florida beach resort.


The Santa Maria Suites Resort resides on the site of a long time Key West treasure. Everything is completely original in homage to our historic designation, the original facade and the restaurant remain intact. Vacation rental homes are not the best choice for everyone-sometimes a bit more panache is in order. The contemporary furnishings and appointments of our retro-inspired guest reception area combine historical significance with a fashion-forward élan. We challenge you to find another Key West hotel with more style and elegance.


What Sets Our Key West Resort Apart:

  • Spacious one and two bedroom guest suites with separate living areas, private balconies and terraces
  • Full kitchens in each room with stove, refrigerator, wine chiller, dishwasher, microwave, coffeemaker, dinnerware and cookware
  • 48-inch flat screen televisions 
  • High-speed wireless Internet access
  • Turndown service with Dove® candies on your pillow and fresh muffins for breakfast
  • Bath & Body Works® bath products
  • Inviting garden area with two heated swimming pools
  • Complimentary smoothies, fresh fruit and bottled water served poolside
  • Chilled towels at the pool
  • Full concierge services
  • On-site Ambrosia Restaurant serving Japanese cuisine
  • Daily happy hour with complimentary wine and hummus
  • Beach access with beach attendant and complimentary towels and chairs

Our Ideal Key West Location

Our location is perfect for exploring Key West—just one block from Duval Street and a short walk to the Atlantic Ocean. A car isn't necessary—it's all within walking distance. If you do drive to Key West, we offer complimentary off-street parking. For vacation rentals in Key West, you shouldn't settle for anything less than the Santa Maria Suites Resort.

Santa Maria Suites Resort 1401 Simonton St Key West, Florida 33040 United States Phone: 305-296-5678